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The Small GTPase Ran formatIsbn:Hardcover - 9780792375104 bankac¿l¿k faaliyetlerinin uzak bir ortamdanRAN: AN ATYPICAL GTPASE Mark G. Rush and Peter D'Eustachio New York University School o Medicine. Department,o Biochemistry New York NY 10016 ABSTRACT GTPases, proteins that bind and hydrolyze GTP (guanosine triphos phate) are critical regulators of many metabolic pathways. Although these proteins are enzymes that catalyze the hydrolysis of GTP to GDP + Pi, their primary function is not the hydrolysis of GTP per se, but rather the coupling of this